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檢驗科許穎教授團隊榮獲四川省醫學會2019年度優秀論文獎

發布時間: 2019-12-31 本文來源: 檢驗科 作者: 檢驗科

2019nian12yue30ri,sichuanshengyixuehuiguanfangwangzhangongshile“sichuanshengyixuehuiguanyu2019nianduyouxiulunwenheqingnianyouxiulunwennijianglunwendegongshi”,yabomaiqiuappjianyankexuyingjiaoshoutuanduibaosongdeyuanchuangxingxueshulunzhu“protective effects of flagellin a n/c against radiation-induced nlr pyrin domain containing 3 inflammasome-dependent pyroptosis in intestinal cells”jingpingxuanronghuo2019nianduyouxiulunwenjiang。


xuyingjiaoshouweilunwentongxunzuozhe,wudongminghehanrongweigongtongdiyizuozhe。gaiwenfabiaozaifangshezhongliuxuetopqikan《international journal of radiation oncology ? biology ? physics》(2018;101(1):107-117)(jcr 1qu,2018nianif=6.203),gaizazhiweimeiguofangshezhongliuxuehuiguanfangqikan,yeneichengwei“hongpizazhi”,zi1975nianchuangkanyilai,zhuyaojujiaoyufenzifusheshengwuxuejizhongliufangliaoxiangguanlinchuangyanjiudengchuangxinxingyanjiu、jishukaifahelinchuangyingyong。

該研究創新性地揭示了細胞焦亡在輻射性炎性損傷中的分子機制,闡述flagellinA N/C蛋白介導的焦亡抑制在放射性腸炎中的潛在治療作用,從而為輻射性損傷機制研究及靶向治療探索了一條新的可能策略。Flagellin A N/C蛋白為該團隊具有自主知識產權的抗輻射藥物,已授權發明專利2項,圍繞該蛋白的前期研究已分別在《Vaccine》《Radiation Research》《Oncology Reports》雜志發表SCI論文3篇。該研究得到了國家自然科學基金、四川省教育廳科研創新團隊及亞博體彩買球科研創新團隊等項目的支持,在本論文的基礎上,許穎教授團隊進一步獲批國家自然科學基金面上項目1項,四川省科技廳項目2項。


許穎教授簡介

xuying,jiaoshou/zhurenjishi,shuodao,xianrenyaboticaimaiqiukejichufuchuchang、yaboappmaiqiujianyanke(sichuanshengjiajiyixuezhongdianxueke—linchuangjianyanzhenduanxue)zhuren,ruidiankaluolinsikayixueyuanboshihou。huopiweidishipisichuanshengxueshuhejishudaitourenhoubeirenxuan,dishierpisichuanshengweishengtingxueshuhejishudaitouren,sichuanshengweishengjiankanglingjunrencai。danrenzhongguoweishengwuxuehuilinchuangweishengwuxuezhuanyeweiyuanhuiqingnianweiyuanhuifuzhurenweiyuan、zhongguokangaixiehuizhongliulinchuangjianyanyubansuizhenduanzhuanyeweiyuanhuichangwuweiyuan,sichuanshengyixuehuijianyanzhuanyeweiyuanhuifuzhurenweiyuan、sichuanshengkangfuyixuehuijianyanzhuanweihuizhurenweiyuandengxueshuzhiwu。zhuchiguojiazirankexuejijin2xiang、shengbujiheshengtingjiketi10yuxiang。fuzedekeyantuanduihuopisichuanshengshengshugaoxiaokeyanchuangxintuanduijiyaboticaimaiqiukeyanchuangxintuanduijianshe。fabiaokeyanlunwen60yupian,qizhong,yidiyizuozhejitongxunzuozhezai《international journal of radiation oncology ? biology ? physics》、《cell death & disease》、《international journal of cancer》dengguojiqikanfabiaoscilunwen13pian,shouquanguojiafamingzhuanli4xiang。zuoweidiyiwanchengrenhuoshengshijiyixuekejijiangge1xiang。zhuyaocongshi: 1、zhongliuzhuanyifenzijizhijibiaozhiwuyanjiu;2、fushexingxibaojiaowangfenzijizhijibaxiangganyucelve;3、weishengwunaiyaojizhi。

(jianyanke)

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